N-propylnorapomorphine   Click here for help

GtoPdb Ligand ID: 934

Abbreviated name: NPA
Compound class: Synthetic organic
Comment: ChEMBL represents this compound with specified stereochemistry with the entry CHEMBL330274.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 43.7
Molecular weight 295.16
XLogP 3.64
No. Lipinski's rules broken 0
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Canonical SMILES CCCN1CCc2c3C1Cc1ccc(c(c1c3ccc2)O)O
Isomeric SMILES CCCN1CCc2c3C1Cc1ccc(c(c1c3ccc2)O)O
InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
D1 receptor Hs Agonist Full agonist 7.4 pKi - 1
pKi 7.4 [1]
D5 receptor Hs Agonist Full agonist 5.9 pKi - 1
pKi 5.9 [1]