Synonyms: emapalumab-lzsg | Gamifant® | NI-0501 | NI0501
emapalumab is an approved drug (FDA (2018))
Compound class:
Antibody
Comment: Emapalumab (NI-0501) is a fully human monoclonal antibody that targets interferon gamma (IFNγ).
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. BLAST peptide anaylsis reveals identical matches with peptides claimed in patent WO2006109191, and in which NI-0501 is confirmed as an exemplary antibody [2]. |
Bioactivity Comments |
IFNγ binding and neutralisation by NI-0501 and results of biological function studies are provided in patent WO2006109191 [2]. |
Selectivity at ligand targets | ||||||||||||||||||||||||||||||||||
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