cabiralizumab   Click here for help

GtoPdb Ligand ID: 9107

Synonyms: BMS-986227 | FPA-008 | FPA008
Immunopharmacology Ligand
Compound class: Antibody
Comment: Cabiralizumab is an investigational humanized monoclonal antibody targeting the receptor tyrosine kinase, CSF1R (Fms). It is being investigated for its potential anti-cancer activity.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. Protein BLAST analysis reveals 100% matches with peptides claimed in patent US20110274683 [1]
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Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
colony stimulating factor 1 receptor Primary target of this compound Hs Antibody Binding >9.0 pKd - 1
pKd >9.0 (Kd <1x10-9 M) [1]