cangitoxin II   Click here for help

GtoPdb Ligand ID: 7568

Synonyms: cangitoxin-2 | cangitoxin-II | CGTX-II
Comment: Sea anemone toxin from Bunodosoma cangicum.
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Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Nav1.1 Hs Gating inhibitor Slows inactivation 6.8 pEC50 - 1
pEC50 6.8 (EC50 1.65x10-7 M) Inhibits inactivation [1]
Voltage: -90.0 mV
Description: hole-cell voltage clamp of human Nav1.1 expressed in human embryonic kidney cell line HEK293.