L-tyrosine   Click here for help

GtoPdb Ligand ID: 4791

Abbreviated name: L-Tyr
PDB Ligand
Comment: Tyrosine is precursor to noradenaline.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 83.55
Molecular weight 181.07
XLogP -1.78
No. Lipinski's rules broken 0
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Canonical SMILES OC(=O)C(Cc1ccc(cc1)O)N
Isomeric SMILES OC(=O)[C@H](Cc1ccc(cc1)O)N
InChI InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
Enzymes Catalysing Reactions with this Compound as a Substrate or Product
Enzyme EC number Reaction Reference
L-Tyrosine hydroxylase
L-Phenylalanine hydroxylase
Tyrosine aminotransferase
iodotyrosine deiodinase
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Monocarboxylate transporter 10
sodium-coupled neutral amino acid transporter 1 1
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields