[3H]Ro154513

Ligand id: 4365

Name: [3H]Ro154513    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 76.27
Molecular weight 326.11
XLogP 2.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
GABAA receptor α4 subunit Hs Allosteric modulator Full agonist - - -
[Binds to: benzodiazepine site]
GABAA receptor α6 subunit Hs Allosteric modulator Full agonist - - -
[Binds to: benzodiazepine site]
Targets where the ligand is described in the comment field
Target Comment