WAY170523 [Ligand Id: 5288] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL327002 (WAY-170523) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| MMP1/Matrix metalloproteinase-1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL332] [GtoPdb: 1628] [UniProtKB: P03956] | ||||||||
| ChEMBL | Inhibition of Matrix Metalloprotease-1 (MMP-1) | B | 5 | pIC50 | >10000 | nM | IC50 | J Med Chem (2004) 47: 3463-3482 [PMID:15214773] |
| MMP13/Matrix metalloproteinase 13 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL280] [GtoPdb: 1637] [UniProtKB: P45452] | ||||||||
| ChEMBL | Inhibition of Matrix Metalloprotease-13 (MMP-13) | B | 7.77 | pIC50 | 17 | nM | IC50 | J Med Chem (2004) 47: 3463-3482 [PMID:15214773] |
| Matrix metalloproteinase 13 in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5327] [UniProtKB: O77656] | ||||||||
| ChEMBL | Inhibitory concentration against MMP-13 of bovine articular cartilage explants | B | 5 | pIC50 | 10000 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 4105-4109 [PMID:16005220] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
