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GluK5

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Target not currently curated in GtoImmuPdb

Target id: 454

Nomenclature: GluK5

Family: Ionotropic glutamate receptors

Contents:

Gene and Protein Information Click here for help
Species TM P Loops AA Chromosomal Location Gene Symbol Gene Name Reference
Human 3 1 980 19q13.2 GRIK5 glutamate ionotropic receptor kainate type subunit 5
Mouse 3 1 979 7 13.73 cM Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2)
Rat 3 1 979 1q21 Grik5 glutamate ionotropic receptor kainate type subunit 5
Previous and Unofficial Names Click here for help
GRIK2 | glutamate receptor KA2 | GluRgamma2 | EAA2 | GLUK2 | glutamate receptor, ionotropic, kainate 5 | glutamate receptor, ionotropic, kainate 5 (gamma 2) | glutamate receptor
Database Links Click here for help
Alphafold Q16478 (Hs), Q61626 (Mm), Q63273 (Rn)
ChEMBL Target CHEMBL2675 (Hs), CHEMBL4041 (Rn)
Ensembl Gene ENSG00000105737 (Hs), ENSMUSG00000003378 (Mm), ENSRNOG00000020310 (Rn)
Entrez Gene 2901 (Hs), 14809 (Mm), 24407 (Rn)
Human Protein Atlas ENSG00000105737 (Hs)
KEGG Gene hsa:2901 (Hs), mmu:14809 (Mm), rno:24407 (Rn)
OMIM 600283 (Hs)
Pharos Q16478 (Hs)
RefSeq Nucleotide NM_002088 (Hs), NM_008168 (Mm), NM_031508 (Rn)
RefSeq Protein NP_002079 (Hs), NP_032194 (Mm), NP_113696 (Rn)
UniProtKB Q16478 (Hs), Q61626 (Mm), Q63273 (Rn)
Wikipedia GRIK5 (Hs)
Natural/Endogenous Ligands Click here for help
L-glutamic acid

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Agonists
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
[3H]SYM2081 Small molecule or natural product Click here for species-specific activity table Ligand is labelled Ligand is radioactive Hs Full agonist - -
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[3H]kainate Small molecule or natural product Click here for species-specific activity table Ligand is labelled Ligand is radioactive Hs Full agonist - -
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domoic acid Small molecule or natural product Click here for species-specific activity table Ligand has a PDB structure Hs Full agonist - -
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dysiherbaine Small molecule or natural product Click here for species-specific activity table Ligand has a PDB structure Hs Full agonist - -
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kainate Small molecule or natural product Click here for species-specific activity table Hs Full agonist - -
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SYM2081 Small molecule or natural product Click here for species-specific activity table Hs Full agonist - -
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