Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	379	8p11.21	FNTA	farnesyltransferase, CAAX box, subunit alpha
Mouse	-	377	8 14.27 cM	Fnta	farnesyltransferase, CAAX box, alpha
Rat	-	377	16q12.4	Fnta	farnesyltransferase, CAAX box, alpha

Previous and Unofficial Names

farnesyltransferase, CAAX box, alpha | farnesyltransferase

Database Links
Alphafold	P49354 (Hs), Q61239 (Mm), Q04631 (Rn)
BRENDA	2.5.1.58
ChEMBL Target	CHEMBL271 (Hs), CHEMBL2096912 (Mm), CHEMBL3301421 (Mm), CHEMBL2095197 (Rn), CHEMBL2111479 (Rn)
Ensembl Gene	ENSG00000168522 (Hs), ENSMUSG00000015994 (Mm), ENSRNOG00000014462 (Rn)
Entrez Gene	2339 (Hs), 14272 (Mm), 25318 (Rn)
Human Protein Atlas	ENSG00000168522 (Hs)
KEGG Enzyme	2.5.1.58
KEGG Gene	hsa:2339 (Hs), mmu:14272 (Mm), rno:25318 (Rn)
OMIM	134635 (Hs)
Pharos	P49354 (Hs)
RefSeq Nucleotide	NM_002027 (Hs), NM_008033 (Mm), NM_012847 (Rn)
RefSeq Protein	NP_002018 (Hs), NP_032059 (Mm), NP_036979 (Rn)
UniProtKB	P49354 (Hs), Q61239 (Mm), Q04631 (Rn)
Wikipedia	FNTA (Hs)

Enzyme Reaction
EC Number: 2.5.1.58

Inhibitor Comments

Note that for farnesyltransferase inhibitors we map the ligand interaction to the beta subunit (FNTB), although the actual active site forms in the centre of the beta subunit overlapped by the alpha subunit.

Immuno Process Associations

Immuno Process:  Cytokine production & signalling