brentuximab vedotin   Click here for help

GtoPdb Ligand ID: 6772

Synonyms: Adcetris® | anti-CD30 ADC SGN-35 | SGN 35
Approved drug Immunopharmacology Ligand
brentuximab vedotin is an approved drug (FDA (2011), EMA (2012))
Compound class: Antibody
Comment: Antibody-drug conjugate (ADC) that combines an anti-CD30 antibody and the drug monomethyl auristatin E (MMAE). The PubChem ID for the MMAE component compound is CID 11542188. The invention of this ADC is claimed in patent US7090843 [4] and the original article describing the parent antibody (C10 or AC10) is [1].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Classification Click here for help
Compound class Antibody
Approved drug? Yes (FDA (2011), EMA (2012))
International Nonproprietary Names Click here for help
INN number INN
9144 brentuximab vedotin
Synonyms Click here for help
Adcetris® | anti-CD30 ADC SGN-35 | SGN 35
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 324
Other databases
GtoPdb PubChem SID 178103378
PubChem SID 178103378
Search PubMed clinical trials brentuximab vedotin
Search PubMed titles brentuximab vedotin
Search PubMed titles/abstracts brentuximab vedotin
Wikipedia Brentuximab_vedotin