Summary of Clinical Use

Prophylaxis of acute organ rejection in adults following cadaveric- or living-donor renal transplantation

Mechanism Of Action and Pharmacodynamic Effects

Abrogates the critical cellular immune response involved in allograft rejection by acting as a functional IL-2 receptor antagonist, thereby inhibiting IL-2-mediated activation of lymphocytes.

External links

For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com European Medicines Agency (EMA)