rilonacept   Click here for help

GtoPdb Ligand ID: 6790

Synonyms: Arcalyst® | IL-1 Trap | interleukin-1 Trap
Approved drug Immunopharmacology Ligand
rilonacept is an approved drug (FDA (2008), EMA (2009))
Compound class: Peptide or derivative
Comment: Rilonacept is a fusion protein consisting of the binding domains of the IL-1 receptor (IL-1R) and the IL-1 receptor accessory protein (IL-1RAcP) linked to the Fc portion of human IgG1.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
IL-1β Primary target of this compound Hs Fusion protein Binding - - - 1-2
⤷ [1-2]