CXCL7   Click here for help

GtoPdb Ligand ID: 830

Synonyms: PPBP
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: CXCL7 (neutrophil-activating peptide 2, NAP-2) is one of the cleavage products of the pro-platelet basic protein (PPBP) gene. Connective tissue activating protein III and beta-thrombogulin are also products of this gene.
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Synonyms Click here for help
PPBP
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
PPBP pro-platelet basic protein Human pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) Beta-TG, beta-thromboglobulin, b-TG1, connective tissue-activating peptide III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2-L1, neutrophil-activating peptide-2, PBP, platelet basic protein, pro-platelet basic protein (chemokine (C-X-C motif) ligand 7), SCYB7, TGB, TGB1, THBGB1
Database Links Click here for help
Specialist databases
GPCRdb Ligand CXCL7
Other databases
Ensembl Gene ENSG00000163736 (Hs)
Entrez Gene 5473 (Hs)
GtoPdb PubChem SID 135651724
Human Protein Atlas ENSG00000163736 (Hs)
OMIM 121010 (Hs)
RefSeq Protein NP_002695 (Hs)
UniProtKB P02775 (Hs)
Wikipedia CXCL7