ulinastatin

Ligand id: 10359

Name: ulinastatin

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Approved drug? Yes (Japan, China)
International Nonproprietary Names
INN number INN
5938 ulinastatin
Synonyms
Miraclid® | Ulinase® | Urinastatin®
Comments
Ulinastatin is considered to be a metabolite of inter-α-trypsin inhibitor (ITI) that is one of the cleavage products from the AMBP precursor protein [3]. Compared to full length ITI, ulinastatin lacks the carboxyterminal RFSN amino acids. Functionally ulinastatin is a protease inhibitor, that plays an important role in physiological and pathological processes, and has notable anti-inflammatory activity [1-2,6]. It can be purified from healthy human urine or produced using recombinant technology.
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
AMBP alpha-1-microglobulin/bikunin precursor Human -
Database Links
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