CPUY192018 [Ligand Id: 9710] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| kelch like ECH-associated protein 1 in Human [GtoPdb: 2757] [UniProtKB: Q14145] | ||||||||
| GtoPdb | Measuerd using a isothermal titration calorimetry (ITC) assay. | - | 7.4 | pKd | 39.8 | nM | Kd | Sci Rep (2016) 6: 26585 [PMID:27215610] |
| GtoPdb | Binding to hKEAP1 in a biolayer interferometry assay. | - | 8.44 | pKd | 3.59 | nM | Kd | J Med Chem (2014) 57: 2736-45 [PMID:24512214] |
| GtoPdb | Measured using a fluorescence polarisation assay. | - | 7.84 | pIC50 | 14.4 | nM | IC50 | J Med Chem (2015) 58: 6410-21 [PMID:26258437] |
| GtoPdb | Value determined using a fluorescence polarization competition assay. | - | 7.54 | pEC50 | 28.6 | nM | EC50 | J Med Chem (2014) 57: 2736-45 [PMID:24512214] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
