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ChEMBL ligand: CHEMBL137814 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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integrin, beta 3 subunit (platelet glycoprotein IIIa, antigen CD61)/integrin, alpha IIb subunit (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)/Integrin alpha-IIb/beta-3 in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2093869] [GtoPdb: 2457, 2441] [UniProtKB: P05106, P08514] | ||||||||
ChEMBL | Inhibitory activity of fibrinogen binding to purified immobilized glycoprotein (fibrinogen receptor). | B | 4.3 | pIC50 | 50000 | nM | IC50 | J Med Chem (1997) 40: 4308-4318 [PMID:9435900] |
ChEMBL | Inhibition of platelet aggregation induced by 20 uM adenosine 5'-diphosphate (ADP) in human platelet rich plasma (h-PRP). | F | 4.6 | pIC50 | 25000 | nM | IC50 | J Med Chem (1997) 40: 4308-4318 [PMID:9435900] |
CCK1 receptor in Rat [GtoPdb: 76] [UniProtKB: P30551] | ||||||||
GtoPdb | - | - | 6.7 | pIC50 | - | - | - | Bioorg Med Chem (2003) 11: 741-51 [PMID:12538004] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]