ChEMBL ligand: CHEMBL1413622
kallikrein related peptidase 14/Kallikrein 14 in Human [ChEMBL: CHEMBL2641] [GtoPdb: 2866] [UniProtKB: Q9P0G3] There should be some charts here, you may need to enable JavaScript!
kallikrein related peptidase 5/Kallikrein 5 in Human [ChEMBL: CHEMBL4447] [GtoPdb: 2375] [UniProtKB: Q9Y337] There should be some charts here, you may need to enable JavaScript!
kallikrein related peptidase 7/Kallikrein 7 in Human [ChEMBL: CHEMBL2443] [GtoPdb: 2377] [UniProtKB: P49862] There should be some charts here, you may need to enable JavaScript!
ST14 transmembrane serine protease matriptase /Matriptase in Human [ChEMBL: CHEMBL3018] [GtoPdb: 2418] [UniProtKB: Q9Y5Y6] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
kallikrein related peptidase 14/Kallikrein 14 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2641] [GtoPdb: 2866] [UniProtKB: Q9P0G3]
ChEMBL	Inhibition of human kallikrein 14 measured after 15 mins at pH 8 by fluorescence assay	B	5.89	pIC50	1290	nM	IC50	Bioorg Med Chem Lett (2013) 23: 4547-4551 [PMID:23849879]
GtoPdb	-	-	5.89	pIC50	1290	nM	IC50	Bioorg Med Chem Lett (2013) 23: 4547-51 [PMID:23849879]
kallikrein related peptidase 5/Kallikrein 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4447] [GtoPdb: 2375] [UniProtKB: Q9Y337]
ChEMBL	Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by double-reciprocal plot analysis	B	5.36	pKi	4400	nM	Ki	Bioorg Med Chem Lett (2013) 23: 4547-4551 [PMID:23849879]
ChEMBL	Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assay	B	6.57	pIC50	270	nM	IC50	Bioorg Med Chem Lett (2013) 23: 4547-4551 [PMID:23849879]
GtoPdb	-	-	6.57	pIC50	270	nM	IC50	Bioorg Med Chem Lett (2013) 23: 4547-51 [PMID:23849879]
kallikrein related peptidase 7/Kallikrein 7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2443] [GtoPdb: 2377] [UniProtKB: P49862]
ChEMBL	Inhibition of human kallikrein 7 measured after 15 mins at pH 8 by fluorescence assay	B	7.4	pIC50	40	nM	IC50	Bioorg Med Chem Lett (2013) 23: 4547-4551 [PMID:23849879]
GtoPdb	-	-	7.4	pIC50	40	nM	IC50	Bioorg Med Chem Lett (2013) 23: 4547-51 [PMID:23849879]
ST14 transmembrane serine protease matriptase /Matriptase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3018] [GtoPdb: 2418] [UniProtKB: Q9Y5Y6]
GtoPdb	-	-	6.24	pIC50	570	nM	IC50	Bioorg Med Chem Lett (2013) 23: 4547-51 [PMID:23849879]
ChEMBL	Inhibition of human matriptase measured after 15 mins at pH 8 by fluorescence assay	B	6.24	pIC50	570	nM	IC50	Bioorg Med Chem Lett (2013) 23: 4547-4551 [PMID:23849879]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]