galanin [Ligand Id: 3593] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • GAL1 receptor in Human [GtoPdb: 243] [UniProtKB: P47211]
  • GAL1 receptor in Mouse [GtoPdb: 243] [UniProtKB: P56479]
  • GAL1 receptor in Rat [GtoPdb: 243] [UniProtKB: Q62805]
There should be some charts here, you may need to enable JavaScript!
  • GAL2 receptor in Human [GtoPdb: 244] [UniProtKB: O43603]
  • GAL2 receptor in Mouse [GtoPdb: 244] [UniProtKB: O88854]
  • GAL2 receptor in Rat [GtoPdb: 244] [UniProtKB: O08726]
There should be some charts here, you may need to enable JavaScript!
  • GAL3 receptor in Human [GtoPdb: 245] [UniProtKB: O60755]
  • GAL3 receptor in Rat [GtoPdb: 245] [UniProtKB: O88626]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GAL1 receptor in Human [GtoPdb: 243] [UniProtKB: P47211]
GtoPdb - - 10.1 pKi 0.08 nM Ki Peptides (1998) 19: 1771-81 [PMID:9880084];
Proc Natl Acad Sci USA (1994) 91: 9780-3 [PMID:7524088];
Neuropeptides (2005) 39: 143-6 [PMID:15944002];
International Journal of Peptide Research and Therapeutics, (2005) 11: 17-27;
Neuropeptides (2009) 43: 187-92 [PMID:19467704];
Neurochem Int (2011) 58: 714-20 [PMID:21333705];
Int J Pept Res (2006) 12: 115-119
GtoPdb - - 9.89 pIC50 0.13 nM IC50 Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GAL1 receptor in Mouse [GtoPdb: 243] [UniProtKB: P56479]
GtoPdb - - 10.33 pKi 0.05 nM Ki FEBS Lett (1997) 411: 225-30 [PMID:9271210];
J Neurochem (1998) 71: 2252-9 [PMID:9832122]
GAL1 receptor in Rat [GtoPdb: 243] [UniProtKB: Q62805]
GtoPdb - - 10.1 pKi 0.08 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Mol Pharmacol (1997) 52: 337-43 [PMID:9281594];
J Mol Neurosci (1995) 6: 33-41 [PMID:8562318];
J Biol Chem (1997) 272: 31949-52 [PMID:9405385];
FEBS Lett (1998) 434: 277-82 [PMID:9742938]
GtoPdb - - 10.01 pIC50 0.1 nM IC50 J Biol Chem (1999) 274: 37041-5 [PMID:10601261];
Br J Pharmacol (2010) 161: 601-13 [PMID:20880399]
GtoPdb - - 9.8 pEC50 0.16 nM EC50 J Biol Chem (1999) 274: 37041-5 [PMID:10601261]
GAL2 receptor in Human [GtoPdb: 244] [UniProtKB: O43603]
GtoPdb - - 8.81 pKi 1.54 nM Ki Int J Pept Res (2006) 12: 115-119;
Peptides (1998) 19: 1771-81 [PMID:9880084];
International Journal of Peptide Research and Therapeutics, (2005) 11: 17-27;
Neuropeptides (2009) 43: 187-92 [PMID:19467704];
Neurochem Int (2011) 58: 714-20 [PMID:21333705];
Biochem Biophys Res Commun (1998) 243: 474-9 [PMID:9480833]
GtoPdb - - 9.12 pIC50 0.76 nM IC50 Peptides (1998) 19: 1771-81 [PMID:9880084];
Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GtoPdb - - 9.47 pIC50 0.34 nM IC50 Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GAL2 receptor in Mouse [GtoPdb: 244] [UniProtKB: O88854]
GtoPdb - - 8.41 pKi 3.9 nM Ki J Neurochem (1998) 71: 2252-9 [PMID:9832122]
GAL2 receptor in Rat [GtoPdb: 244] [UniProtKB: O08726]
GtoPdb - - 9.25 pKi 0.56 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Mol Pharmacol (1997) 52: 337-43 [PMID:9281594];
J Biol Chem (1997) 272: 31949-52 [PMID:9405385];
FEBS Lett (1998) 434: 277-82 [PMID:9742938];
J Neurochem (1998) 71: 2252-9 [PMID:9832122];
Neuropeptides (2005) 39: 143-6 [PMID:15944002]
GtoPdb - - 9.32 pIC50 0.48 nM IC50 J Biol Chem (1999) 274: 37041-5 [PMID:10601261];
Brain Res Mol Brain Res (1997) 51: 49-59 [PMID:9427506];
Br J Pharmacol (2010) 161: 601-13 [PMID:20880399]
GtoPdb - - 8.28 pEC50 5.2 nM EC50 J Biol Chem (1999) 274: 37041-5 [PMID:10601261]
GAL3 receptor in Human [GtoPdb: 245] [UniProtKB: O60755]
GtoPdb - - 8.35 pKi 4.49 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Peptides (1998) 19: 1771-81 [PMID:9880084];
Neuropeptides (2009) 43: 187-92 [PMID:19467704];
Neurochem Int (2011) 58: 714-20 [PMID:21333705];
Int J Pept Res (2010) : 17-22
GAL3 receptor in Rat [GtoPdb: 245] [UniProtKB: O88626]
GtoPdb - - 8.83 pKi 1.47 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
J Biol Chem (1997) 272: 31949-52 [PMID:9405385];
FEBS Lett (1998) 434: 277-82 [PMID:9742938];
Neuropeptides (2005) 39: 143-6 [PMID:15944002]
GtoPdb - - 6.96 pIC50 108.4 nM IC50 Br J Pharmacol (2010) 161: 601-13 [PMID:20880399]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.