ChEMBL ligand: CHEMBL269960
farnesyl diphosphate synthase/Farnesyl diphosphate synthase in Human [ChEMBL: CHEMBL1782] [GtoPdb: 644] [UniProtKB: P14324] There should be some charts here, you may need to enable JavaScript!
Undecaprenyl pyrophosphate synthase in Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) [ChEMBL: CHEMBL1075025] [UniProtKB: Q97SR4] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
farnesyl diphosphate synthase/Farnesyl diphosphate synthase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1782] [GtoPdb: 644] [UniProtKB: P14324]
ChEMBL	Inhibition of human FPPS	B	5.1	pIC50	8000	nM	IC50	Bioorg Med Chem Lett (2008) 18: 1840-1844 [PMID:18295483]
GtoPdb	Inhibition of human FPPS	-	5.1	pIC50	8000	nM	IC50	Bioorg Med Chem Lett (2008) 18: 1840-4 [PMID:18295483]
Undecaprenyl pyrophosphate synthase in Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075025] [UniProtKB: Q97SR4]
ChEMBL	Inhibition of Streptococcus pneumoniae UPPS	B	6.52	pIC50	300	nM	IC50	Bioorg Med Chem Lett (2008) 18: 1840-1844 [PMID:18295483]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]