compound 4e [PMID: 35546685] [Ligand Id: 12122] activity data from GtoPdb

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  • mitogen-activated protein kinase 14 in Human [GtoPdb: 1499] [UniProtKB: Q16539]
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  • mitogen-activated protein kinase 11 in Human [GtoPdb: 1500] [UniProtKB: Q15759]
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  • mitogen-activated protein kinase 12 in Human [GtoPdb: 1501] [UniProtKB: P53778]
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  • mitogen-activated protein kinase 13 in Human [GtoPdb: 1502] [UniProtKB: O15264]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
mitogen-activated protein kinase 14 in Human [GtoPdb: 1499] [UniProtKB: Q16539]
GtoPdb - - 10 pIC50 0.1 nM IC50 J Med Chem (2022) 65: 7170-7192 [PMID:35546685]
mitogen-activated protein kinase 11 in Human [GtoPdb: 1500] [UniProtKB: Q15759]
GtoPdb - - 9.7 pIC50 0.2 nM IC50 J Med Chem (2022) 65: 7170-7192 [PMID:35546685]
mitogen-activated protein kinase 12 in Human [GtoPdb: 1501] [UniProtKB: P53778]
GtoPdb - - 6.03 pIC50 944 nM IC50 J Med Chem (2022) 65: 7170-7192 [PMID:35546685]
mitogen-activated protein kinase 13 in Human [GtoPdb: 1502] [UniProtKB: O15264]
GtoPdb - - 5.39 pIC50 4100 nM IC50 J Med Chem (2022) 65: 7170-7192 [PMID:35546685]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.