BT7480 [Ligand Id: 12060] activity data from GtoPdb

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  • 4-1BB in Human [GtoPdb: 1878] [UniProtKB: Q07011]
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  • nectin cell adhesion molecule 4 in Human [GtoPdb: 3112] [UniProtKB: Q96NY8]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
4-1BB in Human [GtoPdb: 1878] [UniProtKB: Q07011]
GtoPdb Binding affinity for CD137 in the 1:1 format molecule BCY11858, which has the same CD137 Bicycle as BCY11863 but is a 1:2 format construct - 8.43 pKd ~3.7 nM Kd J Med Chem (2022) 65: 9858-9872 [PMID:35819182]
nectin cell adhesion molecule 4 in Human [GtoPdb: 3112] [UniProtKB: Q96NY8]
GtoPdb Binding affinity determined by SPR - 8.29 pKd 5.1 nM Kd J Med Chem (2022) 65: 9858-9872 [PMID:35819182]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.