compound 8u [PMID: 31999451] [Ligand Id: 10682] activity data from GtoPdb

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  • indoleamine 2,3-dioxygenase 1 in Human [GtoPdb: 2829] [UniProtKB: P14902]
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  • signal transducer and activator of transcription 3 in Human [GtoPdb: 2994] [UniProtKB: P40763]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
indoleamine 2,3-dioxygenase 1 in Human [GtoPdb: 2829] [UniProtKB: P14902]
GtoPdb Binding dissociation constant determined for recombinant human IDO1 by SPR analysis. - 7.1 pKd 80 nM Kd J Med Chem (2020) 63: 1544-1563 [PMID:31999451]
signal transducer and activator of transcription 3 in Human [GtoPdb: 2994] [UniProtKB: P40763]
GtoPdb Binding dissociation constant for human STAT3 determined by SPR analysis. - 6.28 pKd 530 nM Kd J Med Chem (2020) 63: 1544-1563 [PMID:31999451]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.