sphingomyelin synthase 2 inhibitor 15w [Ligand Id: 10054] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • sphingomyelin synthase 1 in Human [GtoPdb: 2520] [UniProtKB: Q86VZ5]
There should be some charts here, you may need to enable JavaScript!
  • sphingomyelin synthase 2 in Human [GtoPdb: 2521] [UniProtKB: Q8NHU3]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
sphingomyelin synthase 1 in Human [GtoPdb: 2520] [UniProtKB: Q86VZ5]
GtoPdb Inhibition of purified human SMS1 in vitro. - 4.25 pIC50 56000 nM IC50 J Med Chem (2018) 61: 8241-8254 [PMID:30074791]
sphingomyelin synthase 2 in Human [GtoPdb: 2521] [UniProtKB: Q8NHU3]
GtoPdb Inhibition of purified human SMS2 in vitro. - 7 pIC50 100 nM IC50 J Med Chem (2018) 61: 8241-8254 [PMID:30074791]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.