The IUPHAR Guide to IMMUNOPHARMACOLOGY Disease list

List of immunological diseases and the biological targets contained in GtoPdb they are associated with.
Disease: Activated PI3K delta syndrome 1 target association: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta more details »
Disease X-Refs: OMIM: 615513
Orphanet: ORPHA397596

Disease: Acute lymphocytic leukemia (ALL) 2 target associations: CD3e; CD19 more details »
Disease X-Refs: OMIM: 613065

Disease: Acute myeloid leukemia 2 target associations: KIT proto-oncogene receptor tyrosine kinase; fms related tyrosine kinase 3 more details »
Disease X-Refs: Disease Ontology: DOID:9119
OMIM: 601626
Orphanet: ORPHA519

Disease: Asthma 6 target associations: MMP2; MMP9; MMP8 ... more details »
Disease X-Refs: Disease Ontology: DOID:2841
OMIM: 600807

Disease: Atopic dermatitis 1 target association: INPP5D more details »
Disease X-Refs: Disease Ontology: DOID:3310
OMIM: 603165

Disease: Autoimmune lymphoproliferative syndrome; ALPS 1 target association: Fas more details »
Disease X-Refs: Disease Ontology: DOID:6688
OMIM: 601859
Orphanet: ORPHA3261

Disease: Behcet syndrome 2 target associations: CIITA; nucleotide binding oligomerization domain containing 1 more details »
Disease X-Refs: Disease Ontology: DOID:13241
OMIM: 109650
Orphanet: ORPHA117

Disease: Chronic lymphocytic leukemia 1 target association: CD20 (membrane-spanning 4-domains, subfamily A, member 1) more details »
Disease X-Refs: Disease Ontology: DOID:1040
OMIM: 151400
Orphanet: ORPHA67038

Disease: Colitis 1 target association: 5-HT1A receptor more details »
Disease X-Refs:

Disease: Crohn's disease 1 target association: heat shock protein family A (Hsp70) member 1 like more details »
Disease X-Refs: Disease Ontology: DOID:8778
OMIM: 266600
Orphanet: ORPHA206

Disease: Graft versus host disease 2 target associations: CD80; CD86 more details »
Disease X-Refs:

Disease: Interstitial cystitis 1 target association: INPP5D more details »
Disease X-Refs: Disease Ontology: DOID:13949

Disease: Irritable bowel syndrome 2 target associations: MMP3; MMP9 more details »
Disease X-Refs: Disease Ontology: DOID:9778

Disease: Kawasaki disease 1 target association: Caspase 3 more details »
Disease X-Refs: OMIM: 611775

Disease: Mastocytosis 1 target association: KIT proto-oncogene receptor tyrosine kinase more details »
Disease X-Refs: Disease Ontology: DOID:350

Disease: Multiple sclerosis 2 target associations: BAFF receptor; MMP9 more details »
Disease X-Refs: Disease Ontology: DOID:2377
OMIM: 126200
Orphanet: ORPHA802

Disease: Myelofibrosis 1 target association: Janus kinase 2 more details »
Disease X-Refs: Disease Ontology: DOID:4971
OMIM: 254450
Orphanet: ORPHA824

Disease: non-Hodgkin lymphoma 1 target association: CD20 (membrane-spanning 4-domains, subfamily A, member 1) more details »
Disease X-Refs: Disease Ontology: DOID:0060060
OMIM: 605027

Disease: Osteoarthritis 5 target associations: MMP13; MMP3; ADAMTS5 ... more details »
Disease X-Refs: Disease Ontology: DOID:8398

Disease: Pemphigus 1 target association: CD20 (membrane-spanning 4-domains, subfamily A, member 1) more details »
Disease X-Refs: Disease Ontology: DOID:9182

Disease: Polycythemia vera 1 target association: Janus kinase 2 more details »
Disease X-Refs: Disease Ontology: DOID:8997
OMIM: 263300
Orphanet: ORPHA729

Disease: Psoriasis 2 target associations: CD2; CD6 more details »
Disease X-Refs: Disease Ontology: DOID:8893

Disease: Relapsing-remitting multiple sclerosis 1 target association: CD20 (membrane-spanning 4-domains, subfamily A, member 1) more details »
Disease X-Refs: Disease Ontology: DOID:2378

Disease: Rheumatoid arthritis 11 target associations: BAFF receptor; MMP1; MMP3 ... more details »
Disease X-Refs: Disease Ontology: DOID:7148
OMIM: 180300

Disease: Sjögren's syndrome 1 target association: BAFF receptor more details »
Disease X-Refs: Orphanet: ORPHA378

Disease: Ulcerative colitis 1 target association: heat shock protein family A (Hsp70) member 1 like more details »
Disease X-Refs: Disease Ontology: DOID:8577
OMIM: 266600
Orphanet: ORPHA771

Disease: WHIM syndrome 1 target association: CXCR4 more details »
Disease X-Refs: OMIM: 193670
Orphanet: ORPHA51636