M14: Carboxypeptidase A

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

AE binding protein 1 Show summary »« Hide summary

Carboxypeptidase A1 (pancreatic) Show summary »« Hide summary More detailed page go icon to follow link

Carboxypeptidase A2 (pancreatic) Show summary »« Hide summary

Carboxypeptidase A3 (mast cell) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

1589

Nomenclature

Carboxypeptidase A3 (mast cell)

Previous and unofficial names

tissue carboxypeptidase A | MC-CPA | carboxypeptidase A3 (mast cell) | carboxypeptidase A3, mast cell

Genes

CPA3 (Hs), Cpa3 (Mm), Cpa3 (Rn)

Ensembl ID

ENSG00000163751 (Hs), ENSMUSG00000001865 (Mm), ENSRNOG00000011181 (Rn)

UniProtKB AC

P15088 (Hs), P15089 (Mm), P21961 (Rn)

EC number

3.4.17.1

Carboxypeptidase A4 Show summary »« Hide summary

Carboxypeptidase A5 Show summary »« Hide summary

Carboxypeptidase A6 Show summary »« Hide summary

Carboxypeptidase B1 (tissue) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

1593

Nomenclature

Carboxypeptidase B1 (tissue)

Previous and unofficial names

protaminase | tissue carboxypeptidase B | Cpb | pancreatic carboxypeptidase B1 | carboxypeptidase B1 (tissue)

Genes

CPB1 (Hs), Cpb1 (Mm), Cpb1 (Rn)

Ensembl ID

ENSG00000153002 (Hs), ENSMUSG00000011463 (Mm), ENSRNOG00000030904 (Rn)

UniProtKB AC

P15086 (Hs), P19223 (Rn)

EC number

3.4.17.2

Carboxypeptidase B2 (plasma) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

1594

Nomenclature

Carboxypeptidase B2 (plasma)

Previous and unofficial names

Genes

CPB2 (Hs), Cpb2 (Mm), Cpb2 (Rn)

Ensembl ID

ENSG00000080618 (Hs), ENSMUSG00000021999 (Mm), ENSRNOG00000010935 (Rn)

UniProtKB AC

Q96IY4 (Hs), Q9JHH6 (Mm), Q9EQV9 (Rn)

EC number

3.4.17.20

Carboxypeptidase D Show summary »« Hide summary

Carboxypeptidase E Show summary »« Hide summary

Target Id

1595

Nomenclature

Carboxypeptidase E

Previous and unofficial names

Genes

CPE (Hs), Cpe (Mm), Cpe (Rn)

Ensembl ID

ENSG00000109472 (Hs), ENSMUSG00000037852 (Mm), ENSRNOG00000043387 (Rn)

UniProtKB AC

P16870 (Hs), Q00493 (Mm), P15087 (Rn)

EC number

3.4.17.10

Carboxypeptidase M Show summary »« Hide summary More detailed page go icon to follow link

Carboxypeptidase N, polypeptide 1 Show summary »« Hide summary More detailed page go icon to follow link

Target Id

1597

Nomenclature

Carboxypeptidase N, polypeptide 1

Previous and unofficial names

Genes

CPN1 (Hs), Cpn1 (Mm), Cpn1 (Rn)

Ensembl ID

ENSG00000120054 (Hs), ENSMUSG00000025196 (Mm), ENSRNOG00000013439 (Rn)

UniProtKB AC

P15169 (Hs), Q9JJN5 (Mm), Q9EQV8 (Rn)

EC number

3.4.17.3

Carboxypeptidase N, polypeptide 2 Show summary »« Hide summary

Target Id	1598
Nomenclature	Carboxypeptidase N, polypeptide 2
Previous and unofficial names	ACBP \| carboxypeptidase N, polypeptide 2, 83kD \| carboxypeptidase N subunit 2 \| carboxypeptidase N
Genes	CPN2 (Hs), Cpn2 (Mm), Cpn2 (Rn)
Ensembl ID	ENSG00000178772 (Hs), ENSMUSG00000023176 (Mm), ENSRNOG00000024384 (Rn)
UniProtKB AC	P22792 (Hs), Q9DBB9 (Mm)

Carboxypeptidase O Show summary »« Hide summary

Target Id

1599

Nomenclature

Carboxypeptidase O

Previous and unofficial names

metallocarboxypeptidase C | metallocarboxypeptidase O

Genes

CPO (Hs)

Ensembl ID

ENSG00000144410 (Hs)

UniProtKB AC

Q8IVL8 (Hs)

EC number

3.4.17.-

Carboxypeptidase Q Show summary »« Hide summary

Carboxypeptidase X (M14 family), member 1 Show summary »« Hide summary

Carboxypeptidase X (M14 family), member 2 Show summary »« Hide summary

Target Id	1601
Nomenclature	Carboxypeptidase X (M14 family), member 2
Previous and unofficial names	CPX2 \| cytosolic carboxypeptidase \| metallocarboxypeptidase 2 \| carboxypeptidase X (M14 family)
Genes	CPXM2 (Hs), Cpxm2 (Mm), Cpxm2 (Rn)
Ensembl ID	ENSG00000121898 (Hs), ENSMUSG00000030862 (Mm), ENSRNOG00000015902 (Rn)
UniProtKB AC	Q8N436 (Hs), Q9D2L5 (Mm)

Carboxypeptidase Z Show summary »« Hide summary

How to cite this family page

Database page citation:

M14: Carboxypeptidase A. Accessed on 18/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=743.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.