Top ▲

M12: Astacin/Adamalysin C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

GtoImmuPdb view: ON   

Overview

« Hide

ADAM (A Disintegrin And Metalloproteinase domain containing proteins) metalloproteinases cleave cell-surface or transmembrane proteins to generate soluble and membrane-limited products.

ADAMTS (with thrombospondin motifs) metalloproteinases cleave cell-surface or transmembrane proteins to generate soluble and membrane-limited products.

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

ADAM2 Show summary »

ADAM7 Show summary »

ADAM8 Show summary » More detailed page

ADAM9 Show summary » More detailed page

ADAM10 Show summary » More detailed page

ADAM11 Show summary »

ADAM12 Show summary » More detailed page

ADAM15 Show summary »

ADAM17 Show summary » More detailed page

ADAM18 Show summary »

ADAM19 Show summary »

ADAM20 Show summary »

ADAM21 Show summary »

ADAM22 Show summary »

ADAM23 Show summary »

ADAM28 Show summary »

ADAM29 Show summary »

ADAM30 Show summary »

ADAM32 Show summary »

ADAM33 Show summary » More detailed page

ADAMTS1 Show summary » More detailed page

ADAMTS2 Show summary »

ADAMTS3 Show summary »

ADAMTS4 Show summary » More detailed page

ADAMTS5 Show summary » More detailed page

ADAMTS6 Show summary »

ADAMTS7 Show summary »

ADAMTS8 Show summary »

ADAMTS9 Show summary »

ADAMTS10 Show summary »

ADAMTS12 Show summary »

ADAMTS13 Show summary »

ADAMTS14 Show summary »

ADAMTS15 Show summary »

ADAMTS16 Show summary »

ADAMTS17 Show summary »

ADAMTS18 Show summary »

ADAMTS19 Show summary »

ADAMTS20 Show summary »

bone morphogenetic protein 1 Show summary » More detailed page

Comments

Show »

References

Show »

How to cite this family page

Database page citation:

M12: Astacin/Adamalysin. Accessed on 15/12/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=739.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Enzymes. Br J Pharmacol. 174 Suppl 1: S272-S359.