PDHK family

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

pyruvate dehydrogenase kinase 1 C Show summary »« Hide summary More detailed page go icon to follow link

Target Id	2915
Nomenclature	pyruvate dehydrogenase kinase 1
Previous and unofficial names	pyruvate dehydrogenase kinase, isoenzyme 1 \| pyruvate dehydrogenase kinase
Genes	PDK1 (Hs), Pdk1 (Mm), Pdk1 (Rn)
Ensembl ID	ENSG00000152256 (Hs), ENSMUSG00000006494 (Mm), ENSRNOG00000001517 (Rn)
UniProtKB AC	Q15118 (Hs), Q8BFP9 (Mm)

PDHK2 (pyruvate dehydrogenase kinase 2) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2142

Nomenclature

pyruvate dehydrogenase kinase 2

Common abbreviation

PDHK2

Previous and unofficial names

pyruvate dehydrogenase kinase, isoenzyme 2 | PDK P45 | pyruvate dehydrogenase kinase

Genes

PDK2 (Hs), Pdk2 (Mm), Pdk2 (Rn)

Ensembl ID

ENSG00000005882 (Hs), ENSMUSG00000038967 (Mm), ENSRNOG00000004172 (Rn)

UniProtKB AC

Q15119 (Hs), Q9JK42 (Mm), Q64536 (Rn)

EC number

2.7.11.2

PDHK3 (pyruvate dehydrogenase kinase 3) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2143

Nomenclature

pyruvate dehydrogenase kinase 3

Common abbreviation

PDHK3

Previous and unofficial names

pyruvate dehydrogenase kinase, isozyme 3 | pyruvate dehydrogenase kinase

Genes

PDK3 (Hs), Pdk3 (Mm), Pdk3 (Rn)

Ensembl ID

ENSG00000067992 (Hs), ENSMUSG00000035232 (Mm), ENSRNOG00000012513 (Rn)

UniProtKB AC

Q15120 (Hs), Q922H2 (Mm)

EC number

2.7.11.2

LOC389533 (pyruvate dehydrogenase kinase 4) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2144

Nomenclature

pyruvate dehydrogenase kinase 4

Common abbreviation

LOC389533

Previous and unofficial names

pyruvate dehydrogenase kinase, isozyme 4 | pyruvate dehydrogenase kinase

Genes

PDK4 (Hs), Pdk4 (Mm), Pdk4 (Rn)

Ensembl ID

ENSG00000004799 (Hs), ENSMUSG00000019577 (Mm), ENSRNOG00000009565 (Rn)

UniProtKB AC

Q16654 (Hs), O70571 (Mm), O54937 (Rn)

EC number

2.7.11.2

How to cite this family page

Database page citation:

PDHK family. Accessed on 16/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=596.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.