PAKB subfamily

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Enzymes
Kinases (EC 2.7.x.x)
STE: Homologs of yeast Sterile 7, Sterile 11, Sterile 20 kinases
STE20 family
PAKB subfamily

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

PAK4 (p21 (RAC1) activated kinase 4) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2136

Nomenclature

p21 (RAC1) activated kinase 4

Common abbreviation

PAK4

Previous and unofficial names

p21 (CDKN1A)-activated kinase 4 | p21-activated kinase 4 | p21 protein (Cdc42/Rac)-activated kinase 4

Genes

PAK4 (Hs), Pak4 (Mm), Pak4 (Rn)

Ensembl ID

ENSG00000130669 (Hs), ENSMUSG00000030602 (Mm), ENSRNOG00000019883 (Rn)

UniProtKB AC

O96013 (Hs), Q8BTW9 (Mm)

EC number

2.7.11.1

PAK5 (p21 (RAC1) activated kinase 5) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2138

Nomenclature

p21 (RAC1) activated kinase 5

Common abbreviation

PAK5

Previous and unofficial names

Genes

PAK5 (Hs), Pak5 (Mm), Pak5 (Rn)

Ensembl ID

ENSG00000101349 (Hs), ENSMUSG00000039913 (Mm), ENSRNOG00000005509 (Rn)

UniProtKB AC

Q9P286 (Hs), Q8C015 (Mm), D4A280 (Rn)

EC number

2.7.11.1

PAK6 (p21 (RAC1) activated kinase 6) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2137

Nomenclature

p21 (RAC1) activated kinase 6

Common abbreviation

PAK6

Previous and unofficial names

p21 (CDKN1A)-activated kinase 6 | p21-activated kinase 6 | PAK5 | p21 protein (Cdc42/Rac)-activated kinase 6

Genes

PAK6 (Hs), Pak6 (Mm), Pak6 (Rn)

Ensembl ID

ENSG00000137843 (Hs), ENSMUSG00000074923 (Mm), ENSRNOG00000007925 (Rn)

UniProtKB AC

Q9NQU5 (Hs), Q3ULB5 (Mm)

EC number

2.7.11.1

How to cite this family page

Database page citation:

PAKB subfamily. Accessed on 16/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=548.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.