Sialic acid binding Ig like lectins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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SIGLECs are a family of type I transmembrane proteins that are predominantly expressed by hemopoietic cells.

Targets

Targets of relevance to immunopharmacology are highlighted in blue

SIGLEC-2 (CD22) Show summary » More detailed page

SIGLEC-3 (CD33) C Show summary » More detailed page

SIGLEC8 (sialic acid binding Ig like lectin 8) Show summary » More detailed page

References

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How to cite this family page

Database page citation:

Sialic acid binding Ig like lectins. Accessed on 19/10/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1000.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Overview. Br J Pharmacol. 174 Suppl 1: S1-S16.